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Roninson, Igor
One or more keywords matched the following items that are connected to Roninson, Igor
Item TypeName
Concept Tumor Cells, Cultured
Academic Article The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo.
Academic Article Activation of MDR1 (P-glycoprotein) gene expression in human cells by protein kinase C agonists.
Academic Article Analysis of gene amplification in human tumor cells by in-gel DNA renaturation assay.
Academic Article Autonomously replicating episomes contain mdr1 genes in a multidrug-resistant human cell line.
Academic Article An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene.
Academic Article Decreased expression of the amplified mdr1 gene in revertants of multidrug-resistant human myelogenous leukemia K562 occurs without loss of amplified DNA.
Academic Article Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs.
Academic Article Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines.
Academic Article Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P-glycoprotein.
Academic Article Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA.
Academic Article Involvement of MDR1 P-glycoprotein in multifactorial resistance to methotrexate.
Academic Article Inhibition of cytarabine-induced MDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethylene glycol-fatty acid diesters, novel inhibitors of P-glycoprotein function.
Academic Article Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis.
Academic Article Identification of p53 genetic suppressor elements which confer resistance to cisplatin.
Academic Article 60-Hz electric fields inhibit protein kinase C activity and multidrug resistance gene (MDR1) up-regulation.
Academic Article Efficient recovery and regeneration of integrated retroviruses.
Academic Article P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity.
Academic Article Drug resistance conferred by MDR1 expression in spheroids formed by glioblastoma cell lines.
Academic Article Applications of green fluorescent protein as a marker of retroviral vectors.
Academic Article Altered expression of ubiquitous kinesin heavy chain results in resistance to etoposide and hypersensitivity to colchicine: mapping of the domain associated with drug response.
Academic Article Activation of the LRP (lung resistance-related protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine.
Academic Article Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells.
Academic Article Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements.
Academic Article p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation.
Academic Article A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents.
Academic Article Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs.
Academic Article p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells.
Academic Article A combination of genetic suppressor elements produces resistance to drugs inhibiting DNA replication.
Academic Article Altered activity of MDR-reversing agents on KB3-1 cells transfected with Gly(185)-->Val human P-glycoprotein.
Academic Article Pleiotropic resistance to DNA-interactive drugs is associated with increased expression of genes involved in DNA replication, repair, and stress response.
Academic Article P-glycoprotein-mediated colchicine resistance in different cell lines correlates with the effects of colchicine on P-glycoprotein conformation.
Academic Article Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent.
Academic Article If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells.
Academic Article Retinoid-induced growth arrest of breast carcinoma cells involves co-activation of multiple growth-inhibitory genes.
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